Frontline Health
Troy Duell with Centurion is providing you with health information and guests to elevate your health and help make your life better. Centurion is a pharmaceutical company that chooses to put people over profits and allow science to dictate what products we bring to market. Our goal is to provide products that you can both afford and are beneficial to your health. It doesn't matter how good a product is if you can't afford it. This podcast will provide you with the best health information possible through sharing studies and current data. We will also interview the leading health experts across the country. We will share sides of the story you may not have heard. Our promise to you is to source all of the information we share with you and speak the truth. We hope this truth is used by you and your loved ones to elevate your health and life.
Frontline Health
#105 - KPV: The Tiny Peptide with Powerful Anti-Inflammatory Properties
Could a chain of just three amino acids be the key to fighting chronic inflammation without the side effects of steroids? Meet KPV (lysine-proline-valine), the tiny peptide making big waves in the health community for its remarkable anti-inflammatory properties.
KPV works differently from traditional anti-inflammatories. When your immune system gets triggered—whether from gut issues, skin problems, or injuries—it releases chemicals causing swelling, redness, and pain. KPV intelligently moderates this response, allowing beneficial inflammation while preventing harmful overreactions. It's like having a bouncer that lets the good guests in while keeping troublemakers out.
What makes this peptide particularly exciting is its versatility. For people suffering from chronic gut issues like Crohn's disease or ulcerative colitis, KPV promotes gut healing and reduces intestinal inflammation. Those with skin conditions such as eczema, psoriasis, or acne may find relief through its ability to calm irritated skin and support healing. KPV even shows antimicrobial properties against staph infections and candida, making it potentially valuable for wound healing.
The benefits extend to those with autoimmune conditions, allergic responses like mast cell activation syndrome, and fibromyalgia. Perhaps most remarkably, KPV accomplishes all this at extremely low doses without the concerning side effects associated with many anti-inflammatory medications.
While the research is promising, we emphasize that KPV isn't a magic bullet. Human clinical trials remain somewhat limited, with much evidence coming from animal studies and anecdotal reports. Anyone interested should consult with a healthcare provider experienced in peptide therapies, especially pregnant individuals and those under 18.
Ready to learn more about how this fascinating peptide might help address your chronic inflammatory conditions? Listen now to discover if KPV could be the missing piece in your health journey, and follow us on social media for more cutting-edge health insights that empower you to become your own best health advocate.
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Today on the Frontline Health Podcast.
Speaker 2:So basically KPV is all about quieting down inflammation. So when our immune system gets triggered, whether that's from a drug issue, a gut issue or a skin problem or some kind of injury, it's going to release chemicals that can cause swelling, redness and pain. But KPV comes in and kind of calms those down and shuts them down and allows the good inflammation in, but it keeps out the bad inflammation.
Speaker 1:Welcome to the Frontline Podcast by Centurion Health, where we share health news, tips and insights to help you take ownership of your health. My name is Evan Patrick. With me is Troy Duhl, the founder and CEO of Centurion Health, and today we're diving into a little powerhouse called KPV. It's a short chain of just three amino acids, but don't let it size fool you. This tiny peptide packs a punch when it comes to inflammation, gut health and more.
Speaker 2:Yeah, it really is kind of amazing how something so small can be so powerful. Kpv has shown incredible potential in everything from gut heal, or healing the gut, to really calming an irritated skin and everything else going on.
Speaker 1:Yep, and for anybody who's been listening to us, we've been talking about peptides a lot lately. They're definitely gaining attention in a health and wellness world, but if you're just now joining us, let's rewind for a second Troy. Can you quickly explain what a peptide is in plain English?
Speaker 2:Yeah, so basically peptides are just short chains of amino acids, which means they're the building blocks of proteins in our body, and you can kind of think of them as tiny messengers that the body uses to really just help regulate different processes that are going on in the body. And you can kind of think of them as tiny messengers that the body uses to really just help regulate different processes that are going on in the body, like healing, immune support, that type of stuff. And KPV is just another peptide that does one of those things.
Speaker 1:So where does KPV come from and why should we care?
Speaker 2:It actually comes from something that's made in our body, naturally called alpha MSH, and KPV stands for lysine, proline and valine, which I know you're looking at it going. Shouldn't that be LPV? But no, it should be KPV, because L, if it was LPV, would stand for leucine. Apparently, within the amino acid world, the L was already taken with another one, so they had to go with KPV. But it's that. Alpha-msh is something that they found a long time ago really helped with inflammation in the 80s, but it had side effects like making your skin darker and unwanted side effects that were there and KPV came out of that. So they pulled a shorter peptide out of it and found that just KPV did the same thing without the side effects.
Speaker 1:We love no side effects. Yes, let's talk about what.
Speaker 2:Although I could use a little better tan, so maybe I should be taking the other one.
Speaker 1:I could as well, but I just don't think a tan would look real on either of us. To be honest, Probably not.
Speaker 2:Probably not.
Speaker 1:So let's talk about what KPV actually does in your body.
Speaker 2:Okay, yeah, so basically KPV is all about quieting down inflammation. So when our immune system gets triggered, whether that's from a drug issue, a gut issue or a skin problem or some kind of injury, it's going to release chemicals that can cause swelling, redness and pain. But KPV comes in and kind of calms those down and shuts them down and allows the good inflammation in, but it keeps out the bad inflammation. So KPV will get inside those cells where that inflammation is happening and just say, hey, let's don't overreact, let's make sure that we're still dealing with the situation, but it's not pouring too much gas on that fire. It's allowing the inflammation to come in, create that healing scenario and then getting out and allowing your body not to over-inflame itself.
Speaker 2:So it's basically like a smart anti-inflammatory it knows where to go and what to do without causing side effects like steroids can and what to do without causing side effects, like steroids can, yeah, and the amazing thing is it works at super low doses, so you don't have to take a huge amount of KPV to start getting some of the effects that you're really looking for.
Speaker 1:So, with that said, what is the big deal? Why are people so excited about KPV?
Speaker 2:Well, there are a lot of studies out there that have shown, and then there are a lot of anecdotal scenarios where people who have had gut issues like colitis and it's taken away the colitis and it's really healed the gut that's there.
Speaker 2:So it's going to help reduce that inflammation, it's going to promote healing of the gut specifically and it's going to in some cases it's helped restore some healthy weight. But then on the topical side, it's helped in studies reduce bacteria and yeast like staph and candida, and it's been very, very helpful in wound healing. So I'm sure you could see practical cases of people who have diabetic neuropathy and maybe they have some open wounds in their legs or have diabetes and they have some open wounds. Then this may be an option for them to come in and really start taking on some of those topical skin conditions. We know that orally it's helped with acne, it's helped with psoriasis, so it's going to help with a lot of things out there. And you know there are even some that have suggested that it's going to help with brain inflammation. But some of those studies are fairly early and we don't have a lot of evidence that points that way. But early studies certainly are pretty exciting.
Speaker 1:It's always great when we come across a new supplement or ingredient or, in this case, peptide that can accomplish multiple benefits all at once in this case, gut, skin and immune support specifically but that can also kind of make it difficult for people to narrow down. Okay, is this something that's for me? Is it going to be the most potent thing for my particular issues? So who should be paying the most attention to KPV right now?
Speaker 2:That's a great question and I'll break it down into two different camps. One is the oral or injectable form of people who take KPV. So if you're taking KPV orally or injectable, those that seem to benefit the most are people with chronic gut issues, kind of like Crohn's disease or ulcerative colitis, and that's because we know that it's really helping support that gut and really bring about healing in the gut area. We also know that if you've got some autoimmune or allergic conditions like fibromyalgia, lupus, mass cell activation syndrome, if you've got chronic wounds or arthritis, those seem to work really well. When you're talking about the oral or the injectable form, the topical, on the other hand, really seems to do well with people that have lots of eczema or psoriasis and anybody who may be recovering from surgery and have some slow healing wounds that are there. So those are really the two camps that you want to look at when you're talking about KPV.
Speaker 1:It's very helpful. Thank you for breaking that down, and you know we always want to be careful not to promote anything as a magic bullet out there. We know that, as helpful and beneficial as some of these new peptides can be, KPV included, that they can't do everything to fix our health. So what are the limitations of KPV?
Speaker 2:Absolutely, and I think you make a great point. There is no magic bullet out there and our bodies all respond and react different, no matter if it's a peptide or if it's a prescription product or if it's a supplement or even a diet. Really, we're all going to respond differently. Trials are still limited. Most of them seem to be in animal studies or lab studies and a lot of anecdotal evidence. When you're talking about the human aspect of it, now I would also say if you've got a provider who has worked with peptides in the past or really understands them, that's probably the best place to go when you're talking about KPV or BPC-157 or any other peptide.
Speaker 2:But I also urge people to use caution, especially if you're pregnant or you may be under the age of 18 and maybe smaller in size or stature, because we don't really know how it might affect. Because we don't really know how it might affect. There aren't studies in pregnant individuals and kids, so you don't have a full grasp of what could happen there. That's why I always recommend going with a provider, and there are also a lot of providers who suggest taking it for a few months and then getting off for a month because they don't want you to have your body become totally dependent on it and make sure that you're able to kind of flush it out of your body. Become totally dependent on it and make sure that you're able to kind of flush it out of your body and then start the process all over again.
Speaker 1:Have you come across any real world stories or patients who've used KPV and gotten really good results?
Speaker 2:Absolutely. I've heard several physicians, even who have used it for themselves, who had irritable bowel syndrome and it seemed to really help get their gut back in check. I've heard several who had some other chronic conditions that they said it seemed to really help get them over the top and get them back to good health. You know there are a lot of people who are taking it for mast cell activation syndrome and fibromyalgia and I haven't heard a lot of evidence based on that. But from everything else that I've seen and read, it seems like that is a good area and a new opportunity that's there. And I haven't seen any of the topical piece or heard anything because we haven't dealt with much of the topical piece, but definitely from the gut healing the mast cell and other things like that, we've heard some pretty promising things.
Speaker 1:You've said some great things today about KPV, troy. Just to summarize some of those high points KPV is a naturally occurring peptide that helps calm inflammation, heal the gut, support the skin and even fight off some harmful microbes.
Speaker 2:Yeah, and I think it is super exciting to see where this peptide is going to go and the opportunities that we have to really target problem areas that a lot of us are dealing with and a lot of our population is dealing with, without having to go to steroids or something else that have side effects that none of us really want. So getting the benefits without the side effects is what we're always looking for and this one seems to fit the bill with a lot of these cases.
Speaker 1:Thank you so much, troy, and thank you for listening to this episode of the Frontline Health Podcast by Centurion. As always, we encourage you go out, take ownership of your health today, because you are your best health advocate. If you enjoyed what you heard today on the podcast, please consider leaving us a review. We would love to hear your feedback and connect with you further. You can also follow us on Instagram X, tiktok and YouTube, and, for safe, effective and affordable health and wellness products made in the USA, visit wwwcenturionhealth. Thanks for listening. We'll see you next time.